I was a technical reviewer for this book. So this is not a completely objective review :). But I think if you are someone who is starting off with programming and need to get up to speed with VB 2008, then this will definitely be a very good book to start off on.
It is aimed at college students to be used as a part of a course. So you will find a number of exercises at the end of each chapter etc. But it also covers a lot of ground from a technical standpoint. It covers all differnt kinds of applications, ie. Console Applications, Winform Apps, ASP.NET Web apps and even some of the newer technologies like WPF and Silverlight.
The other thing is that it is based on the Express Suite of IDEs, so you can use this to learn VB on a budget, without the need for the full Visual Studio 2008 IDE.